Neural Engineering and Translation Labs aim to develop an improved understanding of neural circuits deficits in child and adult psychiatric disorders. We apply neural-engineering methods in both animal models and human research to target and repair identified circuit deficits.

Team

Co-Directors
Dr. Jyoti Mishra
Assistant Professor, Department of Psychiatry

Focus: Human research on digital mobile technologies serving as experimental diagnostics and therapeutics in human psychiatric populations, especially children and adolescents.

Dr. Dhakshin Ramanathan
Assistant Professor, Department of Psychiatry

Focus: Neural engineering studies in animal models of neuropsychiatric disorders.

Our research foci intersect in the use of closed loop, brain-computer-interface (BCI) technologies to target and induce plasticity in specific neural circuits underlying cognition.

Technology Leads

Neural Engineering

Alejandro Ojeda    

Mobile Applications

Alankar Misra    
Postdoctoral Fellows

Cognitive Neurophysiology

Nathalie Buscher    
Research Assistants

Human Neuro-Cognition

Vojislav Maric    
Student Interns

Cognitive Neurophysiology

Tianzhi Tang    

Behavior Automation

Ziqi Gan    

Behavior Automation

Shikun Wang    
 

Research

NEATLabs research projects have three major goals:

  1. To better understand typical development of neural circuits underlying cognitive control.

    Our human studies integrate mobile cognitive assessment tools, electroencephalography (EEG) and functional MRI recordings. We are currently developing integrated software-hardware systems for large-scale and affordable mobile monitoring of neural network function in clinic and community settings.

    Our animal studies are implementing a complementary battery of human cognitive tasks in rodents coupled with invasive monitoring of single units and local-field potentials (LFP). These studies aim to understand micro-circuit contributions to the oscillatory neural dynamics underlying cognitive control identified in humans.

  2. To better understand how neural circuits underlying cognitive control are impacted in neuropsychiatric disorders.

    Our human studies currently focus on how adverse childhood experiences and neurodevelopmental disorders such as ADHD (attention deficit hyperactivity disorder) impact cognitive control network function using a combination of EEG and fMRI methods.

    Our animal studies are currently examining rodent models of schizophrenia and traumatic-brain injury to understand how either genetic perturbations in the former, or environmental perturbations in the latter, result in cognitive impairments.

  3. To develop and advance therapeutic technologies for ameliorating network function deficits.

    We are developing and implementing targeted circuit manipulation strategies that include cognitive remediation and self-regulation interventions, integrated with neuromodulation and brain-computer-interface technologies.

 

Publications

2017
2016
2015
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2001
2000
  • Kothekar V, Sahi S, Mishra J. Enzyme selectivity of new cyclooxygenase-2/5 lipoxygenase inhibitors using molecular modeling approach. Indian Journal of Biochemistry & Biophysics 37: 86-96. PMID: 10983419. 2000.
 

News

  • NEATLabs launch at UC San Diego in June 2017! Follow us on Facebook.
 

Funding

UCSD School of Medicine
Veterans Affairs
Burroughs Wellcome Funds
Klingenstein Foundation
Hellman Foundation
NARSAD
 

Positions

Postdoctoral Fellows

We are always looking for talented postdoctoral fellows interested in our integrated research foci. Please contact NEATLabs directors with your cover letter, CV and academic transcript.