Neural Engineering and Translation Labs aim to develop an improved understanding of neural circuits deficits in child and adult psychiatric disorders. We apply neural-engineering methods in both animal models and human research to target and repair identified circuit deficits. Our research spans single neuron & circuit function to behavior in the context of family & community.

Team

Directors
Dr. Jyoti Mishra
Assistant Professor, Department of Psychiatry

Focus: Engineering & research on digital mobile technologies serving as experimental diagnostics and therapeutics in human neuropsychiatric disorders.

Dr. Dhakshin Ramanathan
Assistant Professor, Department of Psychiatry

Focus: Neural engineering studies in animal models of neuropsychiatric disorders.

Technology Leads

Neural Engineering

Alejandro Ojeda    

Mobile Applications

Alankar Misra    
Postdoctoral Fellows

Cognitive Neurophysiology

Nathalie Buscher    

Human Neuro-Cognition

Sarita Silveira    
Graduate Student

Neurofeedback

Frank Orndorff-Plunkett    
Research Assistant

Human Neuro-Cognition

Vojislav Maric    
Undergraduate Interns

Cognitive Neurophysiology

Tianzhi Tang    

Neural Engineering

Ziqi Gan    

Neural Engineering

Punit Mehta    

BCI Analytics

Sovanarung Seng    
 

Cognitive Neurophysiology

Cliff Chang    

Cognitive Neurophysiology

Sidharth Hulyalkar    

BCI Analytics

Yihan Hu    
 
 

Research

NEATLabs research projects have three major goals:

  1. To better understand typical development of neural circuits underlying cognitive control.

    Our human studies integrate mobile cognitive assessment tools, electroencephalography (EEG) and functional MRI recordings. We are currently developing integrated software-hardware systems for large-scale and affordable mobile monitoring of neural network function in clinic and community settings.

    Our animal studies are implementing a complementary battery of human cognitive tasks in rodents coupled with invasive monitoring of single units and local-field potentials (LFP). These studies aim to understand micro-circuit contributions to the oscillatory neural dynamics underlying cognitive control identified in humans.

  2. To better understand how neural circuits underlying cognitive control are impacted in neuropsychiatric disorders.

    Our human studies currently focus on how adverse childhood experiences and neurodevelopmental disorders such as ADHD (attention deficit hyperactivity disorder) impact cognitive control network function using a combination of EEG and fMRI methods.

    Our animal studies are currently examining rodent models of schizophrenia and traumatic-brain injury to understand how either genetic perturbations in the former, or environmental perturbations in the latter, result in cognitive impairments.

  3. To develop and advance closed-loop technologies for ameliorating neural circuit dysfunctions.

    We are developing and implementing targeted circuit manipulation strategies that include cognitive remediation and neural self-regulation interventions, integrated with neuromodulation and brain-computer-interfaces.

 

Publications

2017
2016
2015
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2001
2000
  • Kothekar V, Sahi S, Mishra J. Enzyme selectivity of new cyclooxygenase-2/5 lipoxygenase inhibitors using molecular modeling approach. Indian Journal of Biochemistry & Biophysics 37: 86-96. PMID: 10983419. 2000.
 

News

  • Alejandro's new paper proposes a fast & robust Sparse Bayesian Learning (SBL) algorithm to solve the EEG source imaging problem.
  • Congrats to Ziqi Gan for acceptance in the UCSD Masters in Computer Science program.
  • Alejandro Ojeda awarded the very competitive Chancellor's Research Excellence Scholarship.
  • Jyoti Mishra selected 2017 Travel Awardee by the American College of Neuropsychopharmacology.
  • Sarita Silveira joins NEATLabs on the prestigious Leopoldina Postdoctoral Fellowship.
  • NEATLabs launch at UC San Diego in June 2017!
 

Funding

UCSD School of Medicine
 
Veterans Affairs
 
Burroughs Wellcome Funds
 
 
Hellman Foundation
 
NARSAD
 
 
 

Positions

Postdoctoral Fellows

We are always looking for talented postdoctoral fellows interested in our integrated research foci. Please contact NEATLabs directors with your cover letter, CV and academic transcript.